Drug Interactions With Dexlansoprazole

There are several medications that dexlansoprazole can interact with, including digoxin, ampicillin, iron, and ketoconazole. Dexlansoprazole may decrease the absorption of these various medications into the body, perhaps making them less effective. It is important to talk to your healthcare provider about potential drug interactions before starting GERD treatment.

Dexlansoprazole Drug Interactions: An Overview

Dexlansoprazole (Kapidex™) can potentially interact with a few other medications. Some of the medicines that may lead to drug interactions with dexlansoprazole include (but are not limited to):
 

Dexlansoprazole Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when any of the drugs mentioned above are combined with dexlansoprazole.
 
Ampicillin
Dexlansoprazole may decrease the absorption of ampicillin into the body, perhaps making it less effective. Check with your healthcare provider before taking these medications together.
 
Atazanavir
Dexlansoprazole may decrease the absorption of atazanavir into the body, making it less effective. For this reason, you should not take dexlansoprazole if you are taking atazanavir.
 
Digoxin
Dexlansoprazole may decrease the absorption of digoxin into the body. Your healthcare provider may decide to monitor your digoxin levels (using a simple blood test), especially when you start or stop taking dexlansoprazole.

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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