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Precautions and Warnings With the Dexamethasone Intravitreal Implant

If you have a detached retina, glaucoma, or any allergies, let your healthcare provider know before using the dexamethasone intravitreal implant. Precautions and warnings also apply to people who operate heavy machinery and to women who are pregnant or breastfeeding. If you have an eye infection or advanced glaucoma, you should not use this medication.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using the dexamethasone intravitreal implant (Ozurdex®) if you have:
  • A viral, bacterial, or fungal eye infection
  • A current herpes infection of the eye, or have ever had one
  • Glaucoma
  • A detached retina
  • Endophthalmitis (inflammation inside the eye)
  • Any allergies, including to medications, foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific Dexamethasone Intravitreal Implant Warnings and Precautions

Some warnings and precautions to be aware of with this medication include the following:
  • The dexamethasone intravitreal implant may cause potentially serious problems, including eye infection, inflammation, and increased pressure inside the eye. The risk for these problems is highest in the days following the injection. Contact your healthcare provider immediately if you have a change in vision or if your eye is painful, red, or sensitive to the light.
  • Your healthcare provider will regularly monitor your progress after you receive this medication, especially in the first week following the injection when your risk for potentially serious side effects is highest. Be sure to keep all your follow-up appointments.
  • You may experience temporary blurred vision right after receiving the injection. Do not perform activities that require clear vision, such as driving or operating heavy machinery, until your vision improves.
  • The use of corticosteroids such as the dexamethasone intravitreal implant can cause increased eye pressure, glaucoma, and cataracts. If you experience any vision problems while using this medication, such as loss of vision, clouded vision, or blurred vision, contact your healthcare provider.
  • Steroids can suppress the body's immune system, which may increase the risk for bacterial, viral, or fungal infections of the eye. The dexamethasone intravitreal implant may mask an infection or make a current infection worse.
  • The dexamethasone intravitreal implant may react with a few other medications (see Drug Interactions With the Dexamethasone Intravitreal Implant).
  • This product is a pregnancy Category C medication, which means that it may not be safe for use during pregnancy, although the full risks are currently unknown (see Ozurdex and Pregnancy for more information).
  • It is unknown if the dexamethasone intravitreal implant passes through breast milk. Therefore, if you are breastfeeding or plan to start, check with your healthcare provider before beginning treatment (see Ozurdex and Breastfeeding).

Dexamethasone Intravitreal Implant Information

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