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Precautions and Warnings With Desonide

If you have any allergies, or if you are pregnant or breastfeeding, you may not be able to use desonide. Other precautions for this product include warnings of potential drug interactions. Desonide can also cause complications if used for too long, such as diabetes and Cushing's syndrome. In addition, this medicine may cause your body to stop making its own natural steroids.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using desonide (Desonate®, DesOwen®, Verdeso®) if you:
 
  • Are breastfeeding
  • Are pregnant or thinking of becoming pregnant
  • Have any allergies, including to foods, dyes, or preservatives.
     
You should also be sure to tell your healthcare provider about all of the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 

Specific Desonide Warnings and Precautions

Some warnings and precautions to be aware of with this medication include the following:
 
  • Desonide is a steroid and can cause serious side effects, such as Cushing's syndrome or diabetes. Although this is more likely to occur with oral or injected steroids, it is still possible with topical steroids such as desonide. The more you apply and the longer you use the drug, the more likely these problems become. Covering the cream with a dressing, which is sometimes recommended, may increase the risk.
     
  • If you use this medication for an extended period, be sure to watch for any signs of Cushing's syndrome (a group of symptoms caused by prolonged exposure to steroids), such as:
     
    • A rounded face
    • Unusual body fat distribution (more fat in the trunk, face, and neck, and less fat in the arms and legs)
    • High blood sugar. 
Let your healthcare provider know if you think you have signs of this problem. 
  • Desonide can suppress the body's ability to make natural steroids. Usually, this happens when large doses are used over a long period. In such circumstances, desonide should be stopped slowly to give your body a chance to begin making natural steroids again. If this is not feasible, you might need to be given an oral steroid for a while, after which you will be weaned slowly from the oral steroid.
     
  • Like all steroids, desonide may slow down the growth rate of children and teenagers. Contact your child's healthcare provider if you are concerned about slow growth. In general, children may be more susceptible to side effects of steroids. Close monitoring is necessary for any child receiving long-term steroids in any form.
     
  • Desonide can potentially react with a few other medications (see Drug Interactions With Desonide).
     
  • This product is considered a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are not currently known (see Desonate and Pregnancy, DesOwen and Pregnancy, or Verdeso and Pregnancy).
     
  • It is unknown if desonide passes through breast milk when applied to the skin. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Desonate and Breastfeeding, DesOwen and Breastfeeding, or Verdeso and Breastfeeding).
     

Desonide Drug Information

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