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Side Effects of Desloratadine

Most people do not experience side effects with desloratadine -- if they do occur, they are typically minor. Common side effects include sore throat, muscle pain, and fatigue. Rare side effects include serious allergic reaction and heart palpitations. While taking the drug, let your healthcare provider know about any possible desloratadine side effects you experience or if something just doesn't seem "right."

Side Effects of Desloratadine: An Introduction

As with any medicine, there are possible side effects with desloratadine (Clarinex®); but not everyone who takes the drug will have side effects. In fact, most people tolerate the drug well. When people do develop side effects, in most cases, they are minor, meaning they require no treatment or are easily treated by you or your healthcare provider. In previous research studies, up to 2.4 percent of people stopped taking desloratadine because of side effects.
(This article covers many, but not all, of the possible side effects with desloratadine. Your healthcare provider can discuss a more complete list of desloratadine side effects with you.)

Common Desloratadine Side Effects

Desloratadine has been studied extensively in clinical trials. In these studies, side effects are always documented and compared to side effects that occur in a similar group of people not taking the medicine. Based on these studies, the most common side effects of desloratadine seen in either adults or children included:
  • Nausea -- up to 5 percent
  • Fatigue -- up to 5 percent
  • Sore throat -- up to 4.1 percent
  • Dizziness -- up to 4 percent
  • Urinary tract infection (UTI) -- up to 3.6 percent
  • Muscle pain (myalgia) -- up to 3 percent
  • Dry mouth -- up to 3 percent
  • Excessive tiredness -- up to 2.1 percent.
Other desloratadine side effects, occurring in more than 2 percent of adults or children, included but were not limited to:


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