What Is Desloratadine and Pseudoephedrine Used For?

How Does Desloratadine and Pseudoephedrine Work?

When you come into contact with something you're allergic to, a chain reaction begins inside your body. During this chain reaction, special cells release powerful chemicals. Some of these chemicals can trigger swelling of the nasal passages, leading to nasal congestion (a "stuffy" nose). Other chemicals, such as histamine, can cause sneezing, itching, and irritation.
 
Desloratadine and pseudoephedrine is a combination medication of desloratadine and pseudoephedrine sulfate. Desloratadine (Clarinex®) is part of a class of drugs called antihistamines. As the name implies, it blocks the effects of histamine. This leads to relief of allergy symptoms -- except for nasal congestion. Pseudoephedrine sulfate (Sudafed®) is a decongestant. It works by decreasing the swelling in the nasal passages, which improves nasal congestion.
 

What Is Desloratadine and Pseudoephedrine Used for in Children?

Desloratadine and pseudoephedrine is not approved for use in children. It is only approved for adults and adolescents 12 years of age and older.
 

Off-Label Desloratadine and Pseudoephedrine Uses

On occasion, your healthcare provider may recommend desloratadine and pseudoephedrine for something other than the conditions listed above. This is called an "off-label" use. At this time, there are no universally accepted off-label uses for desloratadine and pseudoephedrine.
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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