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Side Effects of Desloratadine and Pseudoephedrine

Most people do not experience side effects of desloratadine and pseudoephedrine. If they do occur, they are usually minor and easily treated. Common side effects include insomnia, dry mouth, and headache. Among the rare desloratadine and pseudoephedrine side effects that occur in less than 2 percent of people taking the drug are heart palpitations and rapid heart rate.

Desloratadine and Pseudoephedrine Side Effects: An Introduction

As with any medicine, side effects are possible with desloratadine and pseudoephedrine (Clarinex-D®); but not everyone who takes the drug will have side effects. In fact, most people tolerate it quite well. When people do develop side effects, in most cases, they are minor, meaning they require no treatment or are easily treated by you or your healthcare provider. In previous research studies, up to 3.6 percent of people stopped taking the 12-hour dose of desloratadine and pseudoephedrine and 3.4 percent of people stopped taking the 24-hour dose because of side effects.
 
(This article covers many, but not all, of the possible side effects with desloratadine and pseudoephedrine. Your healthcare provider can discuss a more complete list of desloratadine and pseudoephedrine side effects with you.)

  

Common Side Effects of Desloratadine and Pseudoephedrine

Desloratadine and pseudoephedrine has been studied extensively in clinical trials. In these studies, side effects are always documented and compared to side effects that occur in a similar group of people not taking the medicine. Based on these studies, the most common side effects seen in people taking the 12-hour dose included:
 
The most common side effects seen in people taking the 24-hour dose of desloratadine and pseudoephedrine included:
 
  • Dry mouth -- up to 8 percent
  • Headache -- up to 6 percent
  • Insomnia -- up to 5 percent
  • Fatigue -- up to 3 percent
  • Excessive tiredness -- up to 3 percent
  • Sore throat -- up to 3 percent
  • Dizziness -- up to 2 percent.
     
Other side effects of desloratadine and pseudoephedrine (in either the 12-hour or 24-hour doses) that occurred in more than 2 percent of people included but were not limited to:
 
  • Viral infections, such as the common cold or flu
  • Nervousness
  • Nausea
  • Loss of appetite.

 

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Desloratadine and Pseudoephedrine Medication

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