Drug Interactions With Desloratadine and Pseudoephedrine

Drug interactions with desloratadine and pseudoephedrine can change the way your body metabolizes the drugs, increasing their levels in your body. These interactions can occur with ketoconazole, reserpine, and beta blockers like metoprolol, atenolol, and propranolol, among other drugs. If drug interactions with desloratadine and pseudoephedrine are a concern, your doctor may monitor you more closely or prescribe a different medication.

 

An Overview of Drug Interactions With Desloratadine and Pseudoephedrine

Desloratadine and pseudoephedrine (Clarinex-D®) can potentially interact with a number of other medications. Drug interactions with desloratadine and pseudoephedrine can occur with the following drugs, among others:
 
 

Specific Drug Interactions With Desloratadine and Pseudoephedrine

The following sections explain potential drug interactions with desloratadine and pseudoephedrine and the unwanted effects these may cause.
 
Ketoconazole
Taking ketoconazole at the same time as you're taking desloratadine and pseudoephedrine may cause your body to metabolize the medicines differently than intended. This can result in an increased amount of desloratadine and pseudoephedrine in your body. If you are taking these medications together, your healthcare provider may choose to monitor you more closely or make necessary dosing adjustments.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;