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Drug Interactions

This medication may potentially interact with a number of other medicines (see Drug Interactions With Dalteparin).

Overdose Information

People who take too much of this medication may experience bleeding, including dangerous internal bleeding. Seek immediate medical attention if you or someone else may have overdosed on this medication.
(Click Fragmin Overdose for more information.)

How Does It Work?

Dalteparin is a low-molecular-weight heparin medication. Like heparin, dalteparin works to prevent the formation of clots (or the growth of existing clots) by binding to an enzyme in the body known as antithrombin III. In doing so, dalteparin accelerates the activity of antithrombin III.
Because antithrombin III inhibits two clotting factors (known as factor Xa and IIa), dalteparin effectively inhibits these two clotting factors as well. This action helps to reduce clot formation.
Like other "blood thinners," dalteparin does not break down clots. Instead, it slows down clot formation, giving the body a chance to naturally break down the clots.

When and How to Take It

Some general considerations include the following:
  • This medication is given as an injection just under the skin (as a subcutaneous injection) once or twice a day.
  • The injections are usually given in the fatty layer on the abdomen (the "stomach" area), the upper thigh, or the upper area of a buttock.
  • If you are in a hospital, a healthcare provider will probably administer the injection. However, you may be sent home with this medication, in which case you or a caregiver must administer the injections.
  • Make sure your healthcare provider shows you exactly how to inject dalteparin.
  • Do not inject this medication into a muscle. It should be injected into the fat layer under the skin.
  • For this drug to work properly, it must be used as prescribed. You may be increasing your risk for serious problems if you stop taking it too soon.
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Dalteparin Drug Information

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