Side Effects of Colesevelam

Most people have no problems when taking colesevelam; side effects, however, can occur. Nausea, indigestion, and the common cold are among the commonly reported side effects. These are typically minor and easily treated by you or your healthcare provider. Other side effects of colesevelam, such as unexplained muscle pain, tenderness, or weakness, should be reported to your healthcare provider immediately.

 

An Introduction to Colesevelam Side Effects

As with any medicine, side effects are possible with colesevelam hydrochloride (WelChol®). However, not everyone who takes the drug will experience side effects. Most people tolerate it quite well. If side effects do occur, in most cases, they are minor, meaning they require no treatment or are easily treated by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with colesevelam. Your healthcare provider can discuss a more complete list of colesevelam side effects with you.)
 

Side Effects of Colesevelam to Report

Some side effects with colesevelam, while occurring infrequently, are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
 
  • Severe stomach pain with nausea or vomiting
  • Low blood sugar (hypoglycemia) in people with type 2 diabetes
  • High blood pressure (hypertension)
  • High triglycerides
  • Bloody or black, tarry stools
  • Unexplained muscle pain, tenderness, or weakness
  • Difficulty swallowing or a feeling that something is "stuck" in the throat
  • Signs of an allergic reaction, such as:
 
    • An unexplained rash
    • Itching
    • Hives
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing.
 
(Side Effects of Colesevelam Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;