Colesevelam (Cont.)

Alternatives to Colesevelam for High Cholesterol

Lowering cholesterol levels should begin with lifestyle modifications, such as:
 
  • A diet low in cholesterol and saturated fats
  • Limited alcohol use
  • Weight loss
  • Exercise.
 
If lifestyle changes alone do not lower triglyceride or cholesterol levels enough, certain medications, such as colesevelam, may be necessary.
 
Cholesterol treatment is aimed at lowering LDL cholesterol levels enough to reduce the risk of complications associated with high cholesterol (see Effects of High Cholesterol). If you are at a higher risk, you will have a lower LDL goal.
 
(Click High Cholesterol Risk to determine your cholesterol risk and find out what your LDL cholesterol level should be.)
 
For most people, colesevelam is effective at lowering cholesterol. It is also often well tolerated. However, side effects can occur, and people may wish to consider a substitute for colesevelam. These substitutes could include other bile acid sequestrants, statins, or other cholesterol medicines.
 
(Click WelChol Alternatives for more information.)
 

What If I Take an Overdose of Colesevelam?

Since colesevelam is not absorbed into the body, there is little risk of toxic effects, although bothersome digestive side effects may occur. However, if you happen to take too much, you should still seek medical attention.
 

How Should Colesevelam Be Stored?

Colesevelam should be stored at room temperature in a tightly closed container. It should be protected from light and moisture.
 
Keep colesevelam and all medications out of the reach of children.
 
(Colesevelam Continued: Page 6)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;