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Effects of Ciclesonide

Ciclesonide has been evaluated in several different studies for treating nasal allergies. In these studies, the drug helped reduce nasal allergy symptoms, including runny nose, nasal congestion, nasal itching, and sneezing. It is often thought that nasal steroids take longer to start working, compared to other allergy medications.
However, studies have shown that improvements in nasal symptoms usually occur within 1 to 10 days of starting ciclesonide (although the symptoms usually continued to improve further over the next few weeks as well).

When and How to Take It

General considerations for when and how to take ciclesonide include the following:
  • The medication comes in nasal spray and nasal aerosol form. It is usually taken just once a day.
  • Ciclesonide must be primed by spraying the bottle into the air before the first use and again if not used for four to ten days. Be sure to follow the instructions for priming the particular ciclesonide product you are using.


  • The specific instructions for use will depend on the particular ciclesonide product you have been prescribed. Make sure to read the information that came with your prescription, so you know how to properly use the medication.


  • Avoid aiming the spray toward the wall that separates your nostrils (in the middle of your nose, called the nasal septum). Spraying ciclesonide toward the nasal septum increases the risk of nosebleeds. Some people find it easiest to avoid this by holding the bottle in the opposite hand (using the right hand to spray into the left nostril and vice versa).
  • Discard your bottle of ciclesonide spray (Omnaris) after 120 sprays or within four months of removing it from its foil pouch, whichever comes first. Discard ciclesonide nasal aerosol (Zetonna) when there is a zero in the dose indicator window. Even though it may seem like there is medicine left, it does not provide the full dose.


  • For the medication to work properly, it must be taken as prescribed. Ciclesonide will not work if you stop taking it.
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