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Carmustine Implant Side Effects

During clinical studies on carmustine implants, some of the most commonly reported side effects included headaches, seizures, and progression of the cancer. Because this chemotherapy drug can cause potentially dangerous reactions, let your healthcare provider know if you develop anything that "just does not seem right." Such problems may include a severe headache or problems with coordination or balance.

An Introduction to Side Effects of Carmustine Implants

Just like any medicine, carmustine implants (Gliadel®) can cause side effects. Not everyone who receives the drug will experience problems. However, like other chemotherapy medicines, carmustine implants can cause significant side effects in many people. Talk with your healthcare provider about ways to prevent or lessen reactions to this drug.
(This article covers many, but not all, of the possible side effects with carmustine implants. Your healthcare provider can discuss a more complete list with you.)

Serious Carmustine Implant Side Effects

Some side effects of carmustine implants are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling, especially of the mouth, lips, or throat
    • Wheezing
    • Difficulty breathing or swallowing
  • Seizures
  • Paralysis or weakness on one side of the body or face
  • Problems with coordination or balance
  • Changes in vision
  • Signs of a blood clot in the lung, such as:
    • Sudden shortness of breath
    • Coughing
    • Chest pain
  • Signs of infection, such as:
    • Fever
    • Chills
    • Aches and pains
    • Sore throat
    • Shortness of breath
    • Cough
    • Severe headache
    • Stiff neck
    • Fever
    • Chills
  • Changes in personality, emotions, or mood
  • Signs of liver problems, such as:
    • Yellowing of the skin or whites of the eyes (jaundice)
    • Dark urine
    • Pale stool
    • Upper-right abdominal (stomach) pain
  • Numbness, tingling, or burning sensations
  • Changes in vision
  • Difficulty walking, talking, or speaking
  • Severe headache
  • Confusion
  • Swelling of the hands, legs, ankles, feet, or face
  • Opening of your surgical wound, or slow healing of it or other wounds
  • Unexplained bleeding
  • Signs of a blood clot, such as:
    • Redness
    • Swelling
    • Pain
    • Tenderness in a leg.
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Carmustine Implant Information

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