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Carfilzomib Side Effects

If you develop a fever, difficulty breathing, or unusual bleeding while using carfilzomib, contact your healthcare provider right away. Clinical studies have shown that most people who use this chemotherapy drug will experience some type of reaction, such as headaches, fatigue, or diarrhea. However, because carfilzomib side effects may be significant, seek medical attention if you develop anything that just does not seem right.


An Introduction to Side Effects of Carfilzomib

As with any chemotherapy medicine, carfilzomib (Kyprolis™) can cause side effects. In fact, most people will experience some type of reaction to this drug, and some side effects can be quite significant. Talk to your healthcare provider about ways to prevent or lessen reactions to this medicine.
(This article covers many, but not all, of the possible side effects with carfilzomib. Your healthcare provider can discuss a more complete list with you.)

Serious Carfilzomib Side Effects

Some side effects of carfilzomib are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Sudden warmth and redness of the face
    • Itching
    • Unexplained swelling of the face, mouth, or throat
    • Wheezing
    • Difficulty breathing or swallowing
  • Signs of an infection, such as:
  • Unusual bleeding or bruising
  • Blood in the urine or stool
  • Black, tarry stools
  • Signs of anemia, such as:
    • Unusual tiredness
    • Weakness
    • Pale skin
    • Shortness of breath
  • Numbness, tingling, pain, or burning sensations in the hands or feet
  • Muscle weakness or difficulty walking
  • Chest pain, tightness, or pressure
  • Shortness of breath
  • A bluish tinge to your skin or lips
  • A change in how much or how often you urinate
  • A rash or skin reaction at the injection site
  • Shortness of breath or difficulty breathing
  • Swelling of the arms, hands, legs, ankles, or feet
  • Unexplained weight gain
  • Increased blood pressure
  • Persistent or severe nausea and vomiting, especially if you cannot keep food down
  • Yellowing of the skin or whites of the eyes (jaundice)
  • Dizziness, lightheadedness, or fainting
  • Signs of hyperglycemia (high blood sugar levels), such as:
    • Increased thirst
    • Frequent urination
    • Blurred vision.
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Carfilzomib Drug Information

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