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Carfilzomib

Important Information for Your Healthcare Provider

You should talk with your healthcare provider prior to using this medication if you have:
 
  • Kidney disease, such as kidney failure (renal failure)
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • Heart problems, including congestive heart failure, heart block, or a condition known as long QT syndrome
  • Had a heart attack in the last six months
  • Had a herpes zoster (shingles) infection
  • Dehydration or have difficulty drinking enough fluids throughout the day
  • Any allergies, including to foods, dyes, or preservatives.
 
Also, let your healthcare provider know if you are:
   
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 
(Click Precautions and Warnings With Carfilzomib to learn more, including information on who should not use the drug.)
 

Clinical Effects of Carfilzomib

Carfilzomib has been studied in people with multiple myeloma whose disease had become worse after treatment with at least two other anticancer medications. All of the people in the study had previously been treated with medications known as bortezomib (Velcade®) and thalidomide (Thalomid®).
 
In this study, 22.9 percent of people had a complete or partial disappearance of their tumors after carfilzomib treatment. The study did not evaluate whether the medicine reduced symptoms or helped people live longer.
 
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Carfilzomib Drug Information

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