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C1 Esterase Inhibitor Side Effects

In clinical studies, C1 esterase inhibitor was shown to cause headaches, nausea, and a rash, among other side effects. Fortunately, most people tolerate this medicine fairly well, and side effects tend to be minor and easy to treat. However, because allergic reactions and other potentially serious problems can also occur, contact your healthcare provider if you develop anything that does not seem right.


An Introduction to Side Effects of C1 Esterase Inhibitor

Just like any medicine, C1 esterase inhibitor (Berinert®, Cinryze®) can cause side effects. However, not everyone who uses the medication will have problems. In fact, most people tolerate it quite well. If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with C1 esterase inhibitor. Your healthcare provider can discuss a more complete list with you.)

Serious C1 Esterase Inhibitor Side Effects

Some side effects, while occurring infrequently, are potentially serious and should be reported immediately to your healthcare provider. These potential reactions include but are not limited to:
  • New, persistent, or worsening pain or swelling
  • Extreme pain, redness, swelling, or irritation at the injection site
  • Shortness of breath
  • Chest pain or pressure
  • Pain, warmth, or swelling in one or both arms or legs, which could be signs of a blood clot
  • Pain or swelling in the abdomen (stomach)
  • Signs of a stroke, such as:
    • Sudden confusion
    • Trouble speaking, seeing, or walking
    • A sudden, severe headache
    • Sudden weakness, paralysis, or numbness on one side of the body
  • Signs of an allergic reaction, such as:
    • Rash
    • Hives
    • Wheezing
    • Chest tightness
    • Difficulty breathing
    • Swelling of the face, throat, or tongue
    • Dizziness or faintness
    • A rapid heartbeat
    • Blue tinge to the lips, gums, or skin.

C1 Esterase Inhibitor Information

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