Precautions and Warnings With Buprenorphine Injection

There are many precautions and warnings with buprenorphine injections to be aware of, including knowing who should not use this drug. For instance, this medication has abuse potential and may not be suitable for people with a history of substance abuse. Also, several drugs may interact with these injections, so tell your healthcare provider about any other medicines you are taking before starting treatment.

What Should I Tell My Healthcare Provider Before Receiving a Buprenorphine Injection?

Talk with your healthcare provider prior to receiving a
 buprenorphine injection (Buprenex®) if you have:
 
  • A history of drug or alcohol dependence or abuse
  • A history of breathing problems, asthma, chronic obstructive pulmonary disease (COPD), or any other lung disease
  • Heart disease of any kind
  • An irregular heart rhythm (arrhythmia)
  • A very slow heart rate (bradycardia)
  • A head injury, brain tumor, or increased pressure around the brain
  • A history of strokes
  • A history of seizures
  • Problems urinating
  • Low blood pressure (hypotension)
  • Gallbladder or pancreas disease
  • Liver disease, such as cirrhosis, liver failure, or hepatitis
  • Kidney disease, such as kidney failure (renal failure)
  • Any allergies, including to foods, dyes, or preservatives.
 
Also, let your healthcare provider know if you are:
 
  • Breastfeeding
  • Pregnant or thinking of becoming pregnant.
 
Make sure to tell your healthcare provider about any medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 
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Written by/reviewed by: Kristi Monson, PharmD
Last reviewed by: Kristi Monson, PharmD
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