Dosing Information for Buprenorphine InjectionThe buprenorphine injection dosage your healthcare provider recommends will vary, depending on a number of factors, including:
- The type and severity of your pain
- The type and dosage of other pain medications you have been taking
- How you respond to the medication
- Your weight (for children)
- Other medications you are taking
- Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
(Click Buprenorphine Injection Dosage for more information.)
Drug InteractionsThe buprenorphine injection may potentially interact with a number of other medicines (see Drug Interactions With Buprenorphine Injection).
What If I Overdose on This Medication?An overdose of this medication can be quite dangerous and can even lead to death. It is important that you seek immediate medical attention if you or someone else may have overdosed on buprenorphine injections.
(Click Buprenex Overdose for more information.)
How Does It Work?Buprenorphine is an opioid narcotic medication. Buprenorphine binds to a specific type of opioid receptor, called the opioid mu-receptor. Opioid mu-receptors are located throughout the body. While the main buprenorphine effects occur in the central nervous system, buprenorphine can produce effects anywhere opioid mu-receptors are found.
Some of these effects, such as pain relief, are desirable. Other effects are undesirable and cause the side effects associated with buprenorphine injection use. Effects of buprenorphine may include but are not limited to:
- Pain relief
- Changes in mood, including feelings of unease (dysphoria) or unusually pleasant feelings (euphoria)
- Cough suppression
- Slowed or shallow breathing
- Slowing of the digestive tract
- Physical dependence.
Interestingly, buprenorphine is a partial (not full) agonist of mu-receptors. This means that it binds to the receptors, but only partially activates the receptors. This usually translates to less chance of abuse, although this is not always the case.