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Drug Interactions With Buprenorphine and Naloxone

Taking certain medications with buprenorphine and naloxone may result in potentially dangerous complications. Some of these reactions can increase your risk for side effects, such as difficulty breathing, memory loss, and drowsiness. Alcohol, benzodiazepines, and medicines that cause drowsiness are among the products that can lead to drug interactions with buprenorphine and naloxone.

An Overview of Buprenorphine and Naloxone Interactions

Buprenorphine and naloxone (Suboxone®) may potentially interact with a number of other medications. Some of the drugs that may lead to reactions with buprenorphine and naloxone include but are not limited to:
 
  • Alcohol
  • Benzodiazepines, such as:
 
 
  • CYP 3A4 inducer medications, such as:
 
 
  • CYP 3A4 inhibitor medications, such as:
 
 
  • Medications that cause drowsiness, such as:
 
 
  • Monoamine oxidase inhibitors (MAOIs), such as:
 
 
  • Other opioids, such as:
 
 
What Your Pharmacist Wishes You Knew About Chronic Pain Medications

Buprenorphine and Naloxone Drug Information

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