You should talk with your healthcare provider prior to using this medication if you have:
- A condition that causes you to bleed easily
- Rheumatoid arthritis
- Dry eyes
- Any other eye condition
- Had multiple eye surgeries in a short period of time
- Any allergies, including to medications, foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant (see Bromfenac and Pregnancy)
- Breastfeeding (see Bromfenac and Breastfeeding).
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Bromfenac to learn more, including information on who should not use the drug.)
As mentioned previously, bromfenac belongs to a group of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). As the name states, NSAIDs reduce inflammation. They do this by blocking an enzyme known as cyclooxygenase (COX), which is responsible for the production of substances in the body known as prostaglandins.
Prostaglandins have a variety of functions in the body. One of their roles is to activate an inflammatory response, including inflammation in the eye. They also cause pain. By blocking the production of prostaglandins, bromfenac reduces inflammation and pain.
Bromfenac is applied directly to the eye. With normal use, very little, if any, of the drug is absorbed from the eye into the bloodstream.