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Brentuximab Vedotin Side Effects

Among the most commonly reported side effects of brentuximab vedotin are nausea, fatigue, and upper respiratory infections. There are also some potentially serious complications that require immediate medical treatment. Contact your healthcare provider right away if you are undergoing treatment with this drug and develop difficulty swallowing, chest pain, or fever.

An Introduction to Side Effects of Brentuximab Vedotin

Just like any medicine, brentuximab vedotin (Adcetris™) can cause side effects. As with other chemotherapy medicines, the side effects can be significant. Although not everyone who receives the drug will experience problems, most people will have some sort of brentuximab vedotin side effect during treatment. Speak with your healthcare provider about ways to prevent or lessen side effects from this medicine.
(This article covers many, but not all, of the possible side effects with brentuximab vedotin. Your healthcare provider can discuss a more complete list with you.)

Serious Brentuximab Vedotin Side Effects

Some side effects of this drug are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Signs of an allergic reaction or an infusion reaction (a reaction that happens while receiving or soon after receiving your dose), such as:
    • Rash
    • Hives
    • Chills
    • Difficulty breathing or swallowing
    • Nausea
    • Itching
    • Fever
    • Cough
    • Swelling of the mouth, tongue, face, lips, or throat
  • Signs of infection, such as:
    • Fever
    • Chills
    • Aches and pains
    • Cough
    • Sore throat
    • Painful urination
  • Signs of anemia, such as:
    • Unusual tiredness
    • Weakness
    • Pale skin
    • Shortness of breath
  • Unusual bruising or bleeding
  • Black, tarry, or bloody stools
  • Numbness, tingling, or burning sensations in the hands or feet
  • Difficulty moving the hands or feet
  • Muscle weakness or loss of strength
  • Sudden shortness of breath, chest pain, and cough
  • An irregular heartbeat
  • Swelling of the arms, legs, ankles, or feet
  • Severe or persistent vomiting or diarrhea
  • Difficulty thinking, speaking, or walking.
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Brentuximab Drug Information

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