Bosentan Side Effects
Common Side Effects
Bosentan has been studied extensively in clinical trials. In these studies, one group of people received the real medication, while another group was given a placebo (a "sugar pill" with no active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the placebo.
In these studies, the most common bosentan side effects included:
- Respiratory tract infections, such as the common cold -- in up to 22 percent of people
- Headache -- up to 15 percent
- Swelling due to fluid retention, usually in the legs, ankles, or feet -- up to 11 percent
- Chest pain -- up to 5 percent
- Fainting -- up to 5 percent.
Other common reactions, occurring in 3 percent to 4 percent of people, included:
- Flushing (sudden warmth and redness of the face, neck, and chest area)
- Low blood pressure (hypotension)
- Inflammation or infection of the sinuses, which could cause nasal stuffiness
- Joint pain
- Increase in certain liver enzymes
- Feelings of a pounding or racing heartbeat
You may experience some or none of the side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
Therefore, make sure to let your healthcare provider know if you develop any side effects while taking bosentan or if something "just does not seem right." While it may not be related to the medication, your healthcare provider will be able to diagnose and treat the problem.