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Bedaquiline Side Effects

Notify your healthcare provider if you are taking bedaquiline and experience serious side effects, such as a fast heartbeat, fainting, or yellowing of the whites of the eyes or skin. In most cases, however, people do not experience problems with this tuberculosis drug. Some of the most common reactions include nausea, headaches, and a loss of appetite.

 

An Introduction to Side Effects of Bedaquiline

Just like any medicine, bedaquiline (Sirturo™) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with bedaquiline. Your healthcare provider can discuss a more complete list with you.)
 

Serious Bedaquiline Side Effects

Some side effects of bedaquiline should be reported immediately to your healthcare provider. These include but are not limited to:
 
  • A fast or irregular heartbeat
  • Lightheadedness, dizziness, or fainting
  • Signs of liver problems, such as:
    • Loss of appetite
    • Nausea and vomiting
    • Fatigue or excessive tiredness
    • Upper-right abdominal (stomach) pain
    • Itching
    • Dark urine
    • Light-colored stool
    • Yellowing of the skin or whites of the eyes (jaundice)
 
  • Signs of an allergic reaction to bedaquiline, such as:
    • An unexplained rash
    • Hives
    • Unexplained swelling, especially of the mouth, lips, or throat
    • Wheezing
    • Difficulty breathing or swallowing.
 

Bedaquiline Drug Information

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