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What Is Basiliximab Used For?

Adults and children as young as one year old may receive basiliximab after a kidney transplant to help prevent transplant rejection. This medicine works by preventing certain white blood cells from attacking the newly transplanted organ. Basiliximab may also be used for unapproved ("off-label") uses, such as treating psoriasis or atopic dermatitis.

An Overview of Uses for Basiliximab

Basiliximab (Simulect®) is a prescription medication approved to prevent organ rejection in people who are receiving a kidney transplant. It is used in combination with other anti-rejection medications, including cyclosporine (Gengraf®, Neoral®, Sandimmune®) and a corticosteroid.
 
A kidney transplant is a surgical procedure in which a healthy kidney (or donor kidney) is placed into someone who has kidney failure. Donated kidneys can come from a living donor or a nonliving donor (someone who has recently died). After the transplant, the healthy kidney takes over the function of the failing kidney. The failed kidney may or may not be removed during the surgery.
 
After a kidney transplant, the immune system, which is responsible for protecting the body from invaders, recognizes that the newly transplanted kidney is not a natural part of the body and attacks it. This is called transplant rejection. It is important to try to prevent transplant rejection, as it can cause the new kidney to fail. Therefore, people who receive kidney or other organ transplants are given medications to help prevent rejection.
 
Basiliximab is given to help prevent acute kidney rejection, which is rejection that occurs within the first six months of receiving a donor kidney. The medication is given as two doses, four days apart.
 

Basiliximab Drug Information

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