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Precautions and Warnings With Basiliximab

Specific Basiliximab Precautions and Warnings

Some warnings and precautions to be aware of prior to receiving this medication include the following:
  • You must use this medicine under the direction of a healthcare provider who has experience prescribing medications that suppress the immune system, and in treating people who have had an organ transplant.
  • Some people may develop a serious allergic reaction to basiliximab, usually within 24 hours of receiving a dose. A reaction can occur even if you have received this medicine in the past without any problems. Contact your healthcare provider immediately if you experience any signs of an allergic reaction, such as:
    • Dizziness
    • A fast heartbeat
    • Shortness of breath, difficulty breathing, or wheezing
    • A rash
    • Hives
    • Itching
    • Unusual sneezing.
  • Because basiliximab suppresses the immune system, it can make it more difficult for your body to fight an infection. Contact your healthcare provider immediately if you experience any signs of infection, such as:
    • Fever
    • Chills
    • Body aches and pains
    • A sore throat
    • Coughing
    • Pain when urinating.
  • You should know that this medicine might increase your risk for developing certain conditions known as lymphoproliferative disorders, such as lymphoma (a type of cancer of the lymph nodes). Lymphoproliferative disorders occur when the body produces too many lymphocytes (a type of white blood cell).
  • People using basiliximab should not receive live vaccines (see Drug Interactions With Basiliximab). Make sure to talk to your healthcare provider before getting a vaccination during basiliximab treatment.
  • This drug may increase blood sugar levels, which could increase your risk for developing diabetes. Tell your healthcare provider if you develop any symptoms of high blood sugar, such as:
    • Increased thirst
    • Frequent urination
    • Fatigue
    • Blurred vision
    • Confusion.
  • Basiliximab is a pregnancy Category B medication, which means it is generally considered safe for use during pregnancy. Talk to your healthcare provider about the risks and benefits of using this medicine while pregnant (see Simulect and Pregnancy).
  • It is unknown if this medication passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to receiving the drug (see Simulect and Breastfeeding).

Basiliximab Drug Information

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