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Drug Interactions With Basiliximab
If your healthcare provider has recommended basiliximab to prevent kidney transplant rejection, it is important that he or she is aware of all other medications, vitamins, and herbal supplements you are taking. Allergic reactions, infections, or other potentially serious problems could occur if basiliximab is combined with certain drugs. Echinacea, live vaccinations, and tacrolimus are just a few examples of drugs known to interact with basiliximab.
Basiliximab (Simulect®) may interact with a number of other medications. Some of the drugs that can interfere with basiliximab include but are not limited to:
- Certain biologic and immunologic medications, such as:
- Abciximab (ReoPro®)
- Belimumab (Benlysta®)
- Denosumab (Prolia®)
- Leflunomide (Arava®)
- Natalizumab (Tysabri®)
- Pimecrolimus (Elidel®)
- Tacrolimus (Prograf®, Protopic®)
- Trastuzumab (Herceptin®)
- Echinacea
- "Live" vaccinations, such as:
- Chickenpox vaccine (varicella vaccine)
- FluMist® (the nasal vaccine for influenza; the injected vaccine is not live)
- MMR vaccine (measles, mumps, rubella vaccine)
- Polio vaccine
- Rotavirus vaccine
- Smallpox vaccine
- Yellow fever vaccine
- BCG vaccine (used in some countries for tuberculosis)
- Sipuleucel-T (Provenge®).
Written by/reviewed by: Susan Lakey, PharmD, MPH, BCPP
Last reviewed by: Kristi Monson, PharmD