Your age and weight (in children) are some of the factors that your healthcare provider will take into consideration before administering basiliximab. The adult dosage for preventing kidney transplant rejection is usually 20 mg within two hours after transplant surgery, with a second 20-mg dose four days later. Your healthcare provider will administer this medicine using an intravenous (IV) injection or infusion.
An Introduction to Your Dosage of BasiliximabThe dose of basiliximab (Simulect®) your healthcare provider recommends will vary, depending on your age and weight (in children). As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
Basiliximab Dosing GuidelinesThe usual dose of basiliximab for the prevention of kidney transplant rejection in adults is 20 mg within two hours of the transplant surgery, followed by 20 mg four days later.
The usual dosage of basiliximab for the prevention of kidney transplant rejection in children who weigh less than 35 kg (77 pounds) is 10 mg within two hours of the transplant surgery, followed by 10 mg four days later. Children who weigh 35 kg or more (at least 77 pounds) are usually given the normal adult dosage.
Your healthcare provider may recommend you not receive the second basiliximab dosage if you experience a serious allergic reaction after the first dose, or if your transplanted kidney fails before the second dose is given.
General Information on Receiving BasiliximabSome considerations to keep in mind during treatment with basiliximab include the following:
- This medication comes as a powder that is dissolved in fluid and given as an injection into a vein (an intravenous, or IV, injection). You will receive your first dose the day of your surgery and a second dose four days later.
- Basiliximab can be given as an intravenous injection or as an intravenous infusion (a slow IV drip into a vein). If given as an infusion, it can take 20 to 30 minutes to receive your dosage.
- A healthcare provider will administer your injection in a healthcare setting, such as a hospital or clinic.
- For this drug to work properly, it must be used as prescribed. Make sure to keep all of your appointments with your healthcare provider.
- If you are unsure about anything related to your dosage or basiliximab dosing in general, please talk to your healthcare provider or pharmacist.