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Atovaquone/Proguanil

When and How to Take It

Some general considerations to keep in mind during treatment with atovaquone/proguanil include the following:
 
  • This medication comes in tablet form. It is usually taken once a day.
     
  • Take atovaquone/proguanil with food or milk. This helps your body absorb as much of the medicine as possible.
     
  • Be sure to take this medication at the same time each day to keep an even level in your bloodstream.
     
  • For people who have trouble swallowing the tablets, atovaquone/proguanil may be crushed and mixed with condensed milk just before taking it. This may be especially helpful in small children.
     
  • If you vomit within one hour after taking your atovaquone/proguanil dose, you should take another one.
     
  • To prevent malaria, atovaquone/proguanil is usually started one or two days before arriving in a malaria area, during the stay, and for seven days after returning. If you cannot take atovaquone/proguanil for this entire time, you may not be protected from malaria, and may need another antimalarial medication.
     
  • It is important to use protective clothing, bed nets, and insect repellents to protect you from mosquito bites in a malaria area. Atovaquone/proguanil alone may not prevent infection.
     
  • To treat malaria, atovaquone/proguanil is usually taken for three days in a row.
     
  • For the medication to work properly, it must be taken as prescribed.
     

Dosing Information

The dose of atovaquone/proguanil your healthcare provider recommends will vary, depending on a few factors, including:
 
  • Whether you are taking the medication to prevent or to treat malaria
  • Your weight (in children).
     
As is always the case, do not adjust your dose unless your healthcare provider specifically tells you to do so.
 
(Click Atovaquone/Proguanil Dosage for more information.)
 

Atovaquone/Proguanil Drug Information

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