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Atovaquone/Proguanil Dosage

If you are taking atovaquone/proguanil to prevent malaria, your healthcare provider will likely recommend that you take it one to two days before entering a malaria area, daily while in the area, and for seven days after returning. When using it to treat rather than prevent malaria, it is taken for only three days. Each dose of atovaquone/proguanil should be taken with food or milk.

An Introduction to Dosing With Atovaquone/Proguanil

The dose of atovaquone/proguanil (Malarone®) your healthcare provider recommends will vary, depending on few factors, including:
 
  • Whether you are taking the medication to prevent or to treat malaria
  • Your weight (in children).
     
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
 

What Is the Atovaquone/Proguanil Dosage for Treating Malaria?

The standard dosage for treating malaria in adults is four tablets of atovaquone/proguanil 250/100 mg, which provides 1000 mg of atovaquone and 400 mg of proguanil, once a day for three days. The standard dose in children is based on the child's weight. Children weighing over 40 kg (88 pounds) are given the adult dose. As with adults, children take atovaquone/proguanil once a day for three days.
 

What Is the Atovaquone/Proguanil Dosage for Preventing Malaria?

The standard dose for malaria prevention in adults is atovaquone/proguanil 250/100 mg, one tablet once a day. Treatment usually begins one to two days before entering a malaria area, daily while in the area, and for seven days after returning.
 
The usual dosage for preventing malaria in children is based on the child's weight. Children who weigh more than 40 kg (88 pounds) are given the adult dose. Just like adults, children will need to take atovaquone/proguanil before, during, and after travel to prevent malaria.
 

Atovaquone/Proguanil Drug Information

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