Drug Interactions With Atorvastatin

If atorvastatin is combined with medications such as fibrates and niacin, it could cause potentially negative drug interactions. Atorvastatin may also interact with birth control pills, digoxin, and cyclosporine. In addition, the medication may also interact negatively with grapefruit. People taking atorvastatin should not drink grapefruit juice, eat grapefruit, or take supplements containing grapefruit.

An Overview of Atorvastatin Interactions

 Atorvastatin calcium (Lipitor®) can potentially interact with a number of medications. Some of the medicines that can cause drug interactions with atorvastatin include:
 
 
  • Certain antifungal medications, including:
     
    • Fluconazole (Diflucan®)
    • Ketoconazole (Nizoral®)
    • Itraconazole (Sporanox®)
    • Miconazole
    • Posaconazole (Noxafil®)
    • Voriconazole (VFEND®)
 
 
 
(Drug Interactions With Atorvastatin Continued: Page 2)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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