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Drug Interactions With Atorvastatin

Interactions With Atorvastatin Explained

The following sections explain in detail the potentially negative interactions that can occur when atorvastatin is combined with any of the drugs listed above.
 
Birth Control Pills
Taking birth control pills with atorvastatin can increase the level of the hormones in the birth control pills, perhaps increasing your risk of side effects. Be sure to discuss this interaction with your healthcare provider if you are currently using birth control pills.
 
Certain Antifungal Medications
Some antifungal medications may increase the level of atorvastatin in your blood, increasing your risk of muscle problems (see Lipitor and Muscle Pain). Check with your healthcare provider before taking atorvastatin with any of these medications.
 
Certain Antibiotics
Certain antibiotics may increase the level of atorvastatin in your blood, possibly increasing your risk of muscle problems (see Lipitor and Muscle Pain). Others (such as rifampin) may produce unpredictable effects, sometimes decreasing the level of atorvastatin in your blood. Check with your healthcare provider before taking these medications together.
 
Cyclosporine (Gengraf, Neoral, Sandimmune)
Taking cyclosporine and atorvastatin simultaneously may greatly increase the level of atorvastatin in your blood. This can increase your risk of side effects of atorvastatin, including serious muscle problems, such as myopathy or rhabdomyolysis (see Lipitor and Muscle Pain). For people who take cyclosporine, the maximum recommended atorvastatin dosage is 10 mg per day.
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