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Atarax Drug Interactions
Alcohol and certain medications may interact with Atarax. Drug interactions may occur if Atarax is taken with acetylcholinesterase inhibitors, phenothiazine medicines, anticholinergic drugs, or pramlintide. These interactions could increase your risk for developing side effects such as dry mouth, constipation, dry eyes, or difficulty passing urine, or lead to potentially serious problems, such as a dangerous irregular heart rhythm.
Atarax® (hydroxyzine hydrochloride) can potentially interact with several other medications. Some of the medicines that may lead to drug interactions with Atarax include:
- Alcoholic beverages
- Acetylcholinesterase inhibitors, such as:
- Donepezil (Aricept®)
- Galantamine (Razadyne™)
- Rivastigmine (Exelon®)
- Tacrine (Cognex®)
- Anticholinergic drugs, such as:
- Atropine
- Belladonna (Donnatal®, B&O Supprettes®, Bellamine S®)
- Benztropine (Cogentin®)
- Clidinium (Librax®)
- Clozapine (Clozaril®)
- Darifenacin (Enablex®)
- Diphenhydramine (Benadryl®)
- Dicyclomine (Bentyl®)
- Glycopyrrolate (Robinul®)
- Haloperidol (Haldol®)
- Homatropine (Hycodan®)
- Hyoscyamine (Levsin®)
- Ipratropium (Atrovent®)
- Oxybutynin (Ditropan®, Ditropan XL®, Oxytrol®)
- Solifenacin (VESIcare®)
- Scopolamine (Transderm Scop®)
- Tiotropium (Spiriva®)
- Tolterodine (Detrol®, Detrol® LA)
- Other medications that cause drowsiness, such as:
- Antipsychotic medications
- Anxiety medications
- Most antidepressants
- Muscle relaxants
- Narcotic pain relievers
- Sleep medications
- Some antihistamines
- Phenothiazine medications, such as:
- Chlorpromazine (Thorazine®)
- Fluphenazine (Prolixin®)
- Perphenazine (Trilafon®)
- Prochlorperazine (Compazine®, Compro®)
- Thioridazine (Mellaril®)
- Trifluoperazine (Stelazine®)
- Pramlintide (Symlin®).
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD