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Arcalyst Uses

How Does It Work?

Arcalyst works by blocking the actions of interleukin-1 beta (IL-1β), a protein of the immune system that causes inflammation in the body. People with CAPS have increased levels of IL-1β, which leads to inflammation in the body. By blocking the action of IL-1β, Arcalyst reduces the inflammation and symptoms associated with CAPS.
 

Is It Safe for Children to Use Arcalyst?

This product is approved for use in children who are at least 12 years old. It has not been adequately studied in younger children.
 
In animal studies, the drug altered fetal bone development when given to pregnant monkeys. It is unknown whether the medication will also affect bone development in children. Therefore, it is recommended that children who use Arcalyst be monitored for appropriate growth.
 

Can Older Adults Use It?

There were not enough older adults in Arcalyst clinical trials to say for certain that older adults will respond to this drug in the same way as younger age groups. In general, older adults may have an increased risk for certain Arcalyst side effects and may need more careful monitoring.
 

Off-Label Uses for Arcalyst

On occasion, a healthcare provider may recommend this medication for something other than the conditions discussed in this article. This is called an "off-label" use. Arcalyst may be used off-label for the treatment of gout and rheumatoid arthritis.
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Arcalyst Medication Information

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