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Drug Interactions

Aprepitant can potentially interact with a number of other medicines (see Drug Interactions With Aprepitant).

What If I Overdose on This Medicine?

It is not known exactly what to expect from an aprepitant overdose. An overdose is unlikely, as most people are given just a few capsules at a time due to the high cost of the medication. In one case, a person who took too much (1440 mg, compared to the usual dose of 40 to 125 mg) experienced drowsiness and a headache.
If you happen to take too much of this medicine, seek immediate medical attention (see Emend Overdose).

How Should Aprepitant Be Stored?

Aprepitant should be stored at room temperature, away from moisture and heat. The capsules should be stored in an airtight container. Keep this and all other medications out of the reach of children.

What Should I Do If I Miss a Dose?

Tell your healthcare provider if you forgot to take your aprepitant dose before your chemotherapy or surgery. If you do not take your subsequent doses as scheduled, take the medication as soon as you remember. However, if it almost time for your next dose, skip the one you missed and continue with your regular schedule. Do not take a double dose.

Who Makes Aprepitant?

Aprepitant is made by Merck & Co., Inc.

Available Strengths

Aprepitant capsules come in the following strengths:
  • Aprepitant 40 mg
  • Aprepitant 80 mg
  • Aprepitant 125 mg.
The medication also comes in a chemotherapy pack that contains one 125-mg capsule and two 80-mg capsules (which are needed for the recommended dosage for the prevention of nausea and vomiting due to chemotherapy).
An injectable form is also available.
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Aprepitant for Nausea or Vomiting

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