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Ambrisentan and Children

Ambrisentan (Letairis®) is a medication prescribed for the treatment of pulmonary arterial hypertension (PAH), a condition that affects the heart and lungs. It comes as a tablet that is taken once daily. Ambrisentan is not approved for use in children younger than 18 years old, as it has not been adequately studied in this age group. Before using this medicine in a child, talk to your healthcare provider about the potential risks and benefits.
As an endothelin receptor antagonist, ambrisentan works by binding to certain receptors in the body, preventing them from causing the blood vessels to narrow (constrict). This can help improve blood flow and reduce symptoms of PAH.
(Click What Is Ambrisentan Used For? for more details on when this medication is prescribed and how it works to help slow down the progression of pulmonary arterial hypertension.)
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