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Afinitor Side Effects

If you are undergoing treatment with Afinitor, notify your healthcare provider immediately if you have seizures, blurred vision, or difficulty breathing. However, in most cases, reactions to this medicine tend to be minor and easy to treat. Some of the most commonly reported side effects of Afinitor include mouth sores, diarrhea, and fatigue.

An Introduction to Afinitor Side Effects

Just like any medicine, Afinitor® (everolimus) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Afinitor. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects of Afinitor

Afinitor has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people taking the drug were documented and then compared to those that occurred in a similar group of people taking a placebo (a "sugar pill" that does not contain any active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the placebo.
In these studies, the most common Afinitor side effects included:
  • Swelling, ulcers, or sores in the mouth -- in up to 86 percent of people
  • Infections, including infections of the respiratory tract, sinuses, and ears -- up to 82 percent
  • A rash -- up to 59 percent
  • Diarrhea -- up to 50 percent
  • Fatigue -- up to 45 percent
  • Swelling of the arms, hands, legs, ankles, feet, or other areas of the body -- up to 39 percent
  • Abdominal (stomach) pain -- up to 36 percent
  • Weakness -- up to 33 percent
  • Nausea -- up to 32 percent
  • Fever -- up to 32 percent
  • Decreased appetite and weight loss -- up to 30 percent
  • Headaches -- up to 30 percent
  • Coughing -- up to 30 percent
  • Vomiting -- up to 29 percent.
Other common reactions, occurring in 10 to 25 percent of people, included:
  • Abnormal absence of a menstrual period in women.
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Afinitor Medication Information

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